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Intravenous ascorbic acid, commonly known as vitamin C, is a water-soluble vitamin vital for numerous biological functions, including the synthesis of collagen, absorption of iron, and the maintenance of the immune system. Administered directly into the bloodstream, intravenous ascorbic acid provides a rapid way to elevate vitamin C levels in the body, bypassing gastrointestinal absorption barriers that may limit oral intake, particularly in individuals with certain medical conditions or gastrointestinal disturbances. As an antioxidant, ascorbic acid plays a crucial role in protecting cells from oxidative stress caused by free radicals, thereby supporting overall cellular health. Clinical applications of intravenous ascorbic acid have gained interest in the treatment of various health conditions, ranging from chronic infections to the support of cancer therapies. In oncology, high-dose intravenous ascorbic acid is being explored as a potential adjunct therapy, with studies suggesting it may enhance the efficacy of chemotherapy while reducing the side effects experienced by patients. Furthermore, in infectious diseases, particularly severe viral and bacterial infections, intravenous administration of vitamin C may aid in modulating the immune response and reducing inflammation. The delivery method ensures rapid plasma concentrations and consistent therapeutic effects, which can be particularly beneficial in emergency care settings or for patients unable to tolerate oral supplementation. Dosage and administration protocols vary depending on the specific medical condition being treated; however, clinical recommendations often involve high doses that exceed typical dietary requirements. Despite its potential benefits, intravenous ascorbic acid should be administered under medical supervision due to the risk of side effects, such as gastrointestinal disturbances, kidney stones, and in rare cases, hemolytic anemia in those with glucose-6-phosphate dehydrogenase deficiency. Additionally, healthcare providers must consider potential interactions with other medications and individual patient health profiles. Ongoing research continues to evaluate the full range of effects and therapeutic applications of intravenous ascorbic acid, particularly its role in the support of critical care patients and those suffering from chronic illnesses. As the medical community deepens its understanding of vitamin C's pharmacological properties, it remains an area of active investigation, with the hope of optimizing treatment protocols that integrate intravenous ascorbic acid into broader therapeutic frameworks. Overall, intravenous ascorbic acid represents a valuable tool in modern medicine, offering promising potential in enhancing patient care through targeted vitamin C delivery to combat both acute and chronic health challenges. By raising awareness of its applications and benefits, healthcare professionals can better navigate the role of intravenous ascorbic acid in supporting patient health and improving outcomes across diverse clinical scenarios.