×
Please select City And Area.
Best Doctor List Near You for Giant Cell Tumor Of Bone in Sar e pol capital and largest city
Best psoriasis doctors near me
Giant Cell Tumor of Bone (GCT) is a benign yet locally aggressive neoplasm that primarily affects the metaphysis of long bones, particularly around the knee joint, such as the distal femur and proximal tibia, though it can occur in other locations such as the pelvis and spine. Characteristically, it presents as a well-defined lytic bone lesion that can cause significant bone destruction, often leading to the expansion of the bone cortex. GCT is composed of multinucleated giant cells, mononuclear stromal cells, and the presence of a reactive or inflammatory background, which contributes to the tumor's distinctive histological appearance. The multinucleated giant cells are thought to derive from osteoclast precursors, indicating a possible role in bone resorption. This tumor typically manifests in young adults, particularly in individuals between the ages of 20 and 40, and exhibits a slight female predominance. The exact cause of GCT remains uncertain, though it is hypothesized to be related to dysregulation of local osteoclast activity, which may be influenced by various genetic factors and hormonal components. Some studies suggest that alterations in the RANK/RANKL/OPG pathway, which is crucial in bone remodeling, play a vital role in its pathogenesis. Patients often present with localized pain and swelling, which may be mistaken for other conditions such as fractures or joint injuries. As the tumor progresses, it can lead to complications such as joint instability and further bone destruction, making timely diagnosis and treatment essential. Imaging studies, such as X-rays, CT scans, and MRI, are critical for evaluation, revealing a lytic lesion with possible cortical thinning or breakthrough. The treatment of choice for GCT is surgical intervention, typically involving curettage and bone grafting, although more extensive procedures such as resection may be necessary in aggressive cases or those with complications. Adjuvant therapies, such as the use of phenol, liquid nitrogen, or radiotherapy, may be applied to reduce recurrence rates. While GCT is considered benign, it has a propensity for local recurrence, with rates varying depending on the treatment method and the completeness of the resection. A small percentage of cases may undergo malignant transformation, especially after aggressive surgical intervention or if they recur multiple times. Given these potential complications, follow-up is critical to monitor for signs of recurrence or complications, underscoring the importance of a comprehensive management approach for those diagnosed with this tumor. Overall, Giant Cell Tumor of Bone presents unique challenges due to its aggressive nature and the necessity for careful management to prevent recurrence and preserve function.
- Hepatocellular Carcinoma Surgery in Sar e pol capital and largest city
- Cardiac Catheterization Specialist in Sar e pol capital and largest city
- Andrologist in Sar e pol capital and largest city
- Cancer Treatment Specialist in Sar e pol capital and largest city
- Cognitive Neurologist in Sar e pol capital and largest city
- Rehabilitation And Functional Therapy Specialist in Sar e pol capital and largest city
- Crisis Response Medical Expert in Sar e pol capital and largest city
- Gallbladder Surgery in Sar e pol capital and largest city
- Pediatric Leukemia Specialist in Sar e pol capital and largest city
- Pediatrician in Sar e pol capital and largest city
- Homeopathic Physician in Sar e pol capital and largest city
- Interventional Radiology in Sar e pol capital and largest city
- Cardiovascular Physiologist in Sar e pol capital and largest city
- Clinical Pathology Specialist in Sar e pol capital and largest city
- Oncologic Intervention Specialist in Sar e pol capital and largest city
- Heart Rhythm Specialist in Sar e pol capital and largest city
- Menopausal And Geriatric Gynecology in Sar e pol capital and largest city
- Robotic Head And Neck Surgical Oncologist in Sar e pol capital and largest city
- Pediatric ICU Consultant in Sar e pol capital and largest city
- Population Health Specialist in Sar e pol capital and largest city
- Spinal Deformity Specialist in Sar e pol capital and largest city
- Photodynamic Therapy in Sar e pol capital and largest city
- Anal Fissures in Sar e pol capital and largest city
- Ross Procedure in Sar e pol capital and largest city
- Neuro Carpal Tunnel Release Surgery in Sar e pol capital and largest city
- Ileal Conduit Urinary Diversion in Sar e pol capital and largest city
- Aortic Aneurysm Repair in Sar e pol capital and largest city
- Flea Bites Treatments in Sar e pol capital and largest city
- Biological Therapy For Inflammatory Bowel Disease in Sar e pol capital and largest city
- Functional Endoscopic Sinus Surgery (FESS) in Sar e pol capital and largest city
- Minimally Invasive Glaucoma Surgery (MIGS) in Sar e pol capital and largest city
- Sports Medicine in Sar e pol capital and largest city
- Flexor Tendon Anatomy in Sar e pol capital and largest city
- Removal Of Stitches in Sar e pol capital and largest city
- Cervical Conization in Sar e pol capital and largest city
- Crown Lengthening in Sar e pol capital and largest city
- Intrinsic Hand Deformity in Sar e pol capital and largest city
- Labiaplasty in Sar e pol capital and largest city
- Fundectomy in Sar e pol capital and largest city
- Joint Injections in Sar e pol capital and largest city
- Mandibular Osteotomy in Sar e pol capital and largest city
- Pulmonary Rehabilitation in Sar e pol capital and largest city
- Pediatric Glomerulonephritis Immunosuppressive Therapy in Sar e pol capital and largest city
- Gynecologic Imaging Services in Sar e pol capital and largest city
- Obesity Exercise Counseling in Sar e pol capital and largest city
- Home Sleep Testing in Sar e pol capital and largest city
- Pancreas-After-Kidney (PAK) Transplant in Sar e pol capital and largest city
- Geriatric Rehabilitation Services in Sar e pol capital and largest city
- Parasitology in Sar e pol capital and largest city
- Mindfulness and Stress Management Programs in Sar e pol capital and largest city
- Palliative Pain Management in Sar e pol capital and largest city
- Medical Oncology Services in Sar e pol capital and largest city
- PediatricConsultative Services in Sar e pol capital and largest city
- Regulatory Compliance Support in Sar e pol capital and largest city
- Surgical Oncology Services in Sar e pol capital and largest city
- Toxic Substance Testing and Identification in Sar e pol capital and largest city
- Pre-Operative Consultation in Sar e pol capital and largest city
- Tissue Biopsy Analysis in Sar e pol capital and largest city
- Valvuloplasty in Sar e pol capital and largest city
- Neuropathology Consultations in Sar e pol capital and largest city
- CT and MRI Enterography in Sar e pol capital and largest city
- Pediatric Cardiac Surgery in Sar e pol capital and largest city
- Auxiliary Liver Transplant in Sar e pol capital and largest city
- Acoustic Neuroma in Sar e pol capital and largest city
- Covid-19 in Sar e pol capital and largest city
- Earache in Sar e pol capital and largest city
- Fluid From The Ear in Sar e pol capital and largest city
- Covid in Sar e pol capital and largest city
- Labyrinthitis in Sar e pol capital and largest city
- Swimmer's Ear in Sar e pol capital and largest city
- Malaria in Sar e pol capital and largest city
- Eye Irritation in Sar e pol capital and largest city
- Ear Infection in Sar e pol capital and largest city
- Glue Ear in Sar e pol capital and largest city
- Lung Cancer in Sar e pol capital and largest city
- Otitis Media in Sar e pol capital and largest city
- Tinnitus in Sar e pol capital and largest city
- Allergies in Sar e pol capital and largest city
- Deafness in Sar e pol capital and largest city
- Ear Wax in Sar e pol capital and largest city
- Depression in Sar e pol capital and largest city
- Hearing Loss in Sar e pol capital and largest city
- Otosclerosis in Sar e pol capital and largest city
- Vertigo in Sar e pol capital and largest city
- Halitosis in Sar e pol capital and largest city
- Ingrown Toenails in Sar e pol capital and largest city
- Unemployment in Sar e pol capital and largest city
- Effusion Knee in Sar e pol capital and largest city
- Blood Clots in Sar e pol capital and largest city
- Bruises in Sar e pol capital and largest city
- Shoulder Impingement in Sar e pol capital and largest city
- Cysts in Sar e pol capital and largest city
- Coma in Sar e pol capital and largest city
- Skin Infection in Sar e pol capital and largest city
- High Cholesterol in Sar e pol capital and largest city
- Leaning To One Side in Sar e pol capital and largest city
- Janeway Lesions in Sar e pol capital and largest city
- Bellybutton Pain in Sar e pol capital and largest city
- Nail Clubbing in Sar e pol capital and largest city
- Blood In Semen in Sar e pol capital and largest city
- Forgetting Common Words in Sar e pol capital and largest city
- Unclear Speech in Sar e pol capital and largest city
- Inflammatory Bowel Disease in Sar e pol capital and largest city
- Melasma in Sar e pol capital and largest city
- Hyperopia in Sar e pol capital and largest city